In contrast to the Orange OR15, the Mark 5 Thirty-Five is a darker amp.
It has a very rich clean tone, without a lot of edge.
It has a distinctive crunch tone.
And it has a monstrous distortion tone that sustains for a days and days.
The EQ section allows a phenomenal level of tonal control.
I usually put the ’74 Telecaster through this, but also the Strat and the Hamer.